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PR System One REMstar BiPAP Pro with Bi-Flex

BY Philips Respironics  |  Item #DS650S
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Item # DS650S

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Differences Between 50 Series and 60 Series System One Machines
Overview of CPAP Power Cords and Power Supplies
Overview of CPAP DC Cables and Batteries
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PR System One BiPAP Pro with Bi-Flex

Respironics brings "System One" to the new line of REMstar BiPAP machines. The PR BiPAP with Bi-Flex is an intelligent solution that knows when, why, and how changes should occur to consistently and effectively provide optimum sleep therapy. New System One technologies like Humidity Control with Dry Box and Resistance Control for use with any mask, all are helping users achieve effective therapy.

PR System One BiPAP Pro with Bi-Flex

Respironics brings "System One" to the new line of REMstar BiPAP machines. The PR BiPAP with Bi-Flex is an intelligent solution that knows when, why, and how changes should occur to consistently and effectively provide optimum sleep therapy. New System One technologies like Humidity Control with Dry Box and Resistance Control for use with any mask, all are helping users achieve effective therapy.

Learn More About Your New Machine

The PR BiPAP Pro comes standard with carrying case, bag, memory card, manuals and now packaged with the Respironics Performance Tubing.

System One Humidity Control (Optional)

The PR CPAP humidifier and water chamber are breakthroughs for managing rain-out and water damage. System One Humidity Control technology analyzes ambient temperature and patient airflow to reach relative humidity at the mask. Sensors inside and outside the BiPAP machine closely monitor changes in humidity and prevents condensation from forming inside the tube.

Dry Box technology is another advancement in reducing water damage to BiPAPs. The air outlet port has been moved from the side of the humidifier onto the top. The water chamber is outfitted with a one-way valve, between the machine and the humidifier. System One with Dry Box makes it possible for the PR BiPAP machines to be truly spill-free.

System One Resistance Control

Respironics wanted a machine to achieve optimal pressure regardless of whether the mask is nasal, pillow, or full face. Resistance Control is the solution. A numbering system on all of Respironics CPAP masks helps define the variable resistance characteristics. Each number programs the BiPAP to compensate for different mask types. The result? A consistent and reliable pressure, enhanced with all the benefits of Bi-Flex Technology no matter which mask is used.

Bi-Flex Family Technology

Flex Technology is designed to enhance traditional BiPAP therapy; maintaining effective therapy at comfortable pressures. Users new to BiPAP equipment find that Flex Technology makes adapting to therapy easier than typical BiPAP machines. The natural breath-by-breath patterns enhances traditional therapy and improves compliance.

Bi-Flex makes the breathing cycle feel natural and comfortable. Flex Technology allows the PR BiPAP Pro to track each breath and provide pressure relief during three critical points in the breathing cycle. Pressure is reduced by .5 increments during the transition from exhalation to inhalation, inhalation to exhalation and during exhalation.The Bi-Flex setting can be adjusted up to 1.5 H20 for maximum comfort.

Advanced Event Detection

The PR BiPAP Pro is designed to identify symptoms beyond classic OSA parameters such AHI and flow limitations. With the PR system, detection is expand to include data on Snoring, Periodic Breathing and Respiratory Effort-Related Arousals (RERAs). Along with digital Auto-Trak Sensitivity and Flex Technology, the PR BiPAP Pro can detect the breathing cycle and report any variation in breathing patterns, increasing therapy effectiveness.

Digital Auto-Trak Sensitivity is the brains behind Respironics' Flex Technology. A patented algorithm monitors breathing patterns and responds to abnormal pressure changes. On the PR BiPAP's, variable triggers and cycle thresholds are adjusted automatically to provide effective sleep therapy.

Advanced event detection includes:

  • Periodic breathing
  • Clear airway apnea
  • Obstructed airway apnea
  • Hypopnea
  • RERA
  • Flow limitation
  • Vibratory snore
  • Large leak
RERAs differ from a Hypopnea event in that a RERA shows increasing respiratory effort with each breath, culminating in a shift in brain wave activity and not necessarily a result of obstruction. Periodic breathing conditions such as Cheyne-Stokes respiration and central apneas are distinguishable from obstructed apnea or snoring events.

Encore Data Management and Reporting

On-board memory has been added to the BiPAP as well as storing information on a generic SD Memory card and reads through any SD card reader. Use EncoreViewer Software to monitor therapy effectiveness through a series of reports. A new Patient Flow and Event report enables users to view a weekly breakdown on per-breath basis. Patient data is used to identify particular conditions and events with specific colors.

Sound Level: 29 dB

Machine Dimensions: 7 in L x 5.5 in W x 4 in H

Machine Weight: 2.8

Machine Warranty: 2 Years

Default Machine Settings: 4-25cm H2O

Humidification Available: Yes

Humidification Type: Integrated

Exhalation Relief: Yes

Ramp Mode: Yes

DC Capable: Yes

Battery Option: Yes

Auto Altitude Adjustment: Yes

Auto Start: Yes

Auto Stop: Yes

Good For: [object Object]

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  • 24 hour access to our CPAPtalk.com Support Forum
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Manufacturer Note

  • Philips Respironics products are for sale only to patients within the U.S. and not to other third parties or businesses.
  • All services provided by CPAP.com, including advertisement, ordering, sale, delivery, instruction, and setup of the products are performed solely by CPAP.com and independently of the manufacturer.
  • A valid prescription is required for the purchase of this product.

Respironics has removed the "blue light" LED and the new power light is barely visible. No more insomnia from excess system lights; the light can even be turned off within the system settings. The only common part shared with the M series is a brick-style Power Supply. The PR system comes with a separate, external power supply that allows the machine to stay compact.

Manufacturer Warranty
This machine comes with a 2 Year Manufacturer Warranty. CPAP.com will work with the manufacturer on your behalf if the machine needs repairs. Please follow these steps:

  • Contact us at cpap@cpap.com or 1-800-356-5221 to receive an RMA (Return Merchandise Authorization) Number before returning the equipment
  • Include a note with the machine describing the issue you are experiencing, along with your full contact information to include a return shipping address and the RMA number provided to you
  • Ship only the defective items to CPAP.com at 13235 N Promenade Blvd Stafford, TX 77477
  • Do not return accessory items such as the carry bag, hose or power cords
  • Email updates will be sent to keep you informed as the machine moves through the warranty process
  • CPAP.com will contact the manufacturer on your behalf and handle all shipping between us and the manufacturer
  • The repaired or replaced unit will be returned to you. Shipping charges may apply.

Please note: The manufacturer warranty is voided by water damage or misuse of the machine.

Humidifier Modes PR System One Heated Humidifiers Version 1.22 or higher have two modes:

  • Classic
  • System One Humidification

NOTE: The version of software installed on a machine is displayed on the screen when the unit is plugged into an outlet. The Humidification settings are displayed only when a PR System One Heated Humidifier is attached to the machine.

Classic Mode
The CPAP user who wants to control the heat setting on the humidifier should select "Classic" mode settings C1,C2, C3, C4 or C5. The "C" in front of the humidification setting indicates "Classic". This allows you to set the level of humidification.

System One Humidification Mode
The CPAP User who wants to allow the technology of the System One Humidification to set the level of humidification delivered based on the humidity present in the room air should select "System One Humidification". The humidification setting will show 1 - 5 but WITHOUT a "C" preceding the number.

Heating Off
If set to zero "0", the humidifier will act as a Passover Humidifier.

Accessing Humidification Settings:

  1. Humidifier must be attached to the machine
  2. Access the Set Up menu
  3. Scroll down the menu offerings to locate: "System One Humidification"
  4. If set to "On", the technology will set the amount of humidification delivered to the system based on the setting of 1 -5 with 1 being the least and 5 being the most
  5. If set to "Off", the user controls the heat setting based on C1-C5 with C1 being the lowest heat and C5 being the highest heat.
360
Universal Power

This system operates automatically between 110v and 240v AC. When traveling either inside or outside the USA, there are no switches to switch or fuses to change. The machine will automatically sense what voltage is needed and set itself to run on that power.

The user will need to adapt the plug that goes into the wall to fit the style of outlet socket that is being used. This is simply done with a Power Adapter Plug kit. This is the same type of plug adapter that would be used with a hair dryer or an electric shaver. World Traveler Power Adapter Plugs.

Universal 12 Volt DC Power Cord

This machine come equipped with a DC plug on the back of the unit. This allows the user to connect the CPAP to an external DC battery source. The machine can be powered by plugging the 12volt DC Power Cord into a cigarette lighter plug. This is ideal for traveling by car, boat, or recreational vehicle that is equipped with a cigarette lighter plug.

C-100 Travel Battery Pack for CPAP Machines

Weighing in at only 1.16 pounds the C-100 Battery is a terrific option for travel. Plus, the C-100 comes with a DC cable and connector peg suitable for use with the PR System One REMstar BiPAP Pro with Bi-Flex PR System One REMstar BiPAP Pro with Bi-Flex so no need to purchase a separate DC cable. This lithium ion battery meets UN Manual Test and Criteria requirements for travel. The C-100 Pack includes many accessories and a handy carry case designed to allow the the cords to be attached with the battery inside the case.

Respironics Battery Kit with Universal 12 Volt DC Cable

This portable battery pack is an external lead acid battery that is the ultimate in power, portability and convenience. This battery kit comes with the Respironics battery and the 12 Volt DC Power Cord (connects CPAP to cigarette lighter socket).
What is the difference BiPAP and BiPAP ST?
A BiPAP (also referred to as a BiLevel or VPAP) delivers two set pressures, a higher pressure for inhalation and a lower pressure for exhalation.

BiPAP and BiPAP ST machines are similar, as they are both designed to provide the same airway pressure. The difference between a BiPAP and a BiPAP ST is the Spontaneous Timed feature. The ST responds to the user when the minimum number of breaths per minute has not been met. This machine ensures all breaths occur by triggering the user to take another breath within the minute.

For example, a BiPAP might be set at the following:
  • Inhalation Pressure - 10
  • Exhalation Pressure - 5
In this case, a BiPAP will provide an IPAP of 10 and EPAP of 5.

A BiPAP ST might be set at the following:
  • Inhalation Pressure - 10
  • Exhalation Pressure - 5
  • 12 BPM (Breath Per Minute)
Similarly to the regular BiPAP, the BiPAP ST will provide an IPAP of 10 and EPAP of 5, and will additionally monitor if you inhale 12 times within the minute. Please Note: The ST will not breathe for you, rather it will prompt the user to take a breath.
How do I choose the machine that is right for me?
We provide our customers with many tools to make informed decisions about their machine purchases. Options include:
How can I compare different machines?
We work very hard to provide many different ways for our customers to compare products. Here are the machine product guides we have created and maintain:
  • CPAP Machine Comparison Guide. This guide stacks up every CPAP machine we sell, feature by feature. If you don't know the meaning of a feature, click the question mark for a definition. The links below will take you to the most popular CPAPs, or all CPAP machines we sell.

    Compare Most Popular CPAP Machines

    Compare All CPAP Machines

  • Auto Adjusting Machine (APAP) Comparison Guide. This guide stacks up every APAP machine we sell, feature by feature. If you don't know the meaning of a feature, click the question mark for a definition. The links below will take you to the most popular APAPs, or all APAP machines we sell.

    Compare Most Popular APAP Machines

    Compare All APAP Machines

  • BiPAP, VPAP and BiLevel Comparison Guide. This guide stacks up every BiPAP machine we sell, feature by feature. If you don't know the meaning of a feature, click the question mark for a definition. The links below will take you to the most popular BiPAPs, or all BiPAP machines we sell.

    Compare Most Popular BiPAP Machines

    Compare All BiPAP Machines
What comes with my machine?
Machines come with a six foot hose, power cord, at least one filter, and manuals. Most manufacturers include a carrying case which is designed specifically for their equipment. CPAP, APAP, and BiPAP machines do not come with a delivery system or mask. CPAP masks must be purchased separately.

To see the list of what specifically comes with each machine, you can Browse for a machine. Then on the product page, click the "Specs" tab to see a full list of what comes with the machine.

Which CPAP masks work on which machines?

Any mask will work with any machine, with one important exception. The ResMed AirMini is only compatible with certain ResMed CPAP masks. Compatible masks for the AirMini are as follows:

  • ResMed AirFit™ N20 Nasal Mask
  • ResMed AirFit™ F20 Full Face
  • ResMed AirTouch™ F20 Full Face
  • ResMed AirFit™ P10 Nasal Pillow

When considering another CPAP, APAP or BiPAP machine from ResMed or any other manufacturer, mask compatibility extends to all brands. The AirMini uses non-standard tubing to connect the machine to the mask, and is the primary reason why other masks won't work with the AirMini. Despite this issue, many of our customers consider the AirMini to be an excellent machine.

What does a BiPAP prescription need to say?
A BiPAP prescription must contain all of the following information:
  • One of the following words or phrases: "BiPAP", "BiLevel", "VPAP"
  • Your physician's contact information
  • Your physician's signature
  • The patient's full name
  • Your inspiration pressure (Also called IPAP or breathing in pressure)
    • Example: IPAP 13 CM/H20
    • Example: IPAP 13
    • Example: IPAP 4 CM/H20
    • Example: IPAP 4
  • Your expiration pressure (Also called EPAP or breathing out pressure)
    • Example: EPAP 13 CM/H20
    • Example: EPAP 13
    • Example: EPAP 18 CM/H2O
    • Example: EPAP 18

Here are some of our top selling BiPAP machines:

IntelliPAP BiLevel Machine with SmartCode
AirCurve™ 10 S BiLevel Machine with HumidAir™ Heated Humidifier
DreamStation BiPAP Pro Machine
+ See More
What is exhalation relief?
Exhalation relief is a comfort feature which reduces the air flow at the time of exhalation, making the breathing process more natural.

The following are the different types of exhalation relief names by manufacturer.

  • Philips Respironics = C-Flex, C-Flex+, A-Flex and Bi-Flex
  • Resmed = EPR (Expiratory Pressure Relief)
  • 3B Medical = RESlex
  • Apex Medical = PVA (Pressure Variation Algorithm) Pressure Relief
  • Curative Medical = EUT (Expiratory Unloading Technology)
  • DeVilbiss = SmartFlex
  • Fisher & Paykel = SensAwake Technology
  • Human Design Medical = Z-Breathe
  • Somnetics = EZEX

Here are some machines with an exhalation relief feature:

Transcend Auto miniCPAP™ Machine with EZEX
PR System One REMStar 60 Series Auto with Bluetooth
AirSense™ 10 AutoSet CPAP Machine with HumidAir™ Heated Humidifier
+ See More
What is Bi-Flex?
Bi-Flex is a feature that makes breathing back against CPAP pressure easier to do. Bi-Flex pressure relief technology offers pressure relief at the transition from exhalation to inhalation, at the transition from inhalation to exhalation, and during exhalation to make BiPAP therapy more like natural breathing.

Bi-Flex Easy Breathing Technology Visual Graph Bi-Flex Easy Breathing Technology Visual Graph

Here are some machines with Bi-Flex:

DreamStation BiPAP Auto Machine
PR System One REMStar 60 Series BiPAP Auto with Bluetooth
What is the difference between Bi-Flex and C-flex?
C-Flex only works at the start of an exhale. Bi-Flex works during the transition from exhalation to inhalation, the transition from inhalation to exhalation and during exhalation.
What maintenance is required on machines?
The only care a CPAP, APAP or BiPAP machine requires is to clean or change the filters at the air intake. This keeps the internal parts from accumulating dust. Fine paper filters should be changed out every 30 days, or when they appear soiled. Foam washable filters should be rinsed with clear running water once a week, allowed to air dry, and reinserted.

Here are some other suggested actions to care for your machine:
  • Keep the area around your machine clean by removing any dust from the area to improve the air quality delivered to your machine and to you.
  • Keep the air intake of the machine unblocked. Curtains, bedding, and papers can easily block the air intake of your machine, reducing the airflow.
  • If a humidifier is used with your therapy, do not pick up the machine with the humidifier attached. With most machines it is easy to spill water from the humidifier chamber into the machine causing damage. Manufacturer warranties are voided by water damage to the machine. To avoid this, remove the chamber from the humidifier and then remove the humidifier from the machine rather than transporting them together.
  • If a humidifier is used, empty the water from the chamber every morning. Accidents happen. If a family pet or family member moves the machine and humidifier with water in the chamber it is more likely that water could be spilled into your machine. Water damage to a machine voids the manufacturer warranty.

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When you shop with us, we want you to be confident that you are receiving the best available price. If this items goes on sale or you spot an online or retail competitor with a lower price within seven days of your purchase, let us know, and we will credit you the difference.

"Super helpful, fast shipping, friendly assistance, great selection, I love this company."

- Verified Customer, 10/25/22

★★★★★

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Manufacturer
Philips Respironics
ResMed
React Health
Warranty
2 Years
2 Years
Sound Level
29 dB
< 26 dB
Quiet
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★★★★★

Budget Friendly Bi-pap

Verified purchase | Dec. 12, 2012 | Verified CPAP.com Customer
This machine is a simple, no frills Bi-pap that delivers my therapy and has a simple ramp function (though I personally want it on full blast when I go to sleep). The first company I was referred to wanted to charge me DOUBLE the cost of this machine (and it turned out they were giving me the EXACT SAME model!). On top of that they were going to bill my insurance for a portion of the cost so the true cost had to be even higher! CPAP.com saved me literally 50% on this machine and I couldn't be more thrilled!
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★★★★★

Verified purchase | Aug. 16, 2012 | Verified CPAP.com Customer
The machine is easy enough to use. The setup was fairly easy as well.
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