ResMed
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ResMed AirSense 10 AutoSet CPAP Machine
ResMed AirSense 10 AutoSet CPAP Machine

ResMed AirSense 10 AutoSet CPAP Machine

(4.7 stars) · 295 reviews | FAQs
$960.00

This product requires a prescription before shipment.

Free Shipping Over $50

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60 Night Risk Free

Product Overview

If you want a CPAP that just works, ResMed’s AirSense 10 AutoSet is the safe, steady choice. It reads your breathing in real time, adjusts pressure to what you need, and keeps things quiet so you and your bed partner can sleep.

Built-in humidification helps fight dryness, while Bluetooth pairing with the myAir™ app gives you nightly scores so you can see how you’re doing.

This is the machine people keep for years because it’s easy to live with: a clear screen, quiet motor, and customizable comfort features that make therapy feel more natural from night one.

What's Included

*Your order comes with everything needed to safely power and run your machine. However, your mask must be purchased separately.

  • AirSense 10 AutoSet
  • ClimateLine Hose
  • Water Chamber
  • Power Supply
  • Disposable Filter
  • Travel Bag
  • User Manual
What Masks Can I Use?

The AirSense 10 works with most standard CPAP masks from any major manufacturer, including nasal, nasal pillow, and full-face masks.

Already have a mask? It will almost certainly work unless it was designed for the AirMini travel CPAP.

Starting fresh? Our CPAP Guides can match you to the right fit.

Shipping & Support

CPAP.com Guarantee
60-day returns
 — even if used. Full refund (excl. shipping fees). Contact our CPAP Guides to start a return.

  • Free shipping on orders over $50 to all 50 states. Orders before 4 PM CST (Mon–Fri) ship same day.
  • Arrives in 5–10 business days via ground shipping.
  • 2-year warranty from Resmed covering defects in materials and workmanship.

Federal law requires us to have a valid prescription on file before we ship your item. Don't have a prescription? Don't worry — we can help. Expired? We'll help you renew it.

Have questions?

Our CPAP Guides are here for you.

Call 1-800-356-5221

For over 10 years, AirSense 10 has set the standard for CPAP therapy.

Product image for AirSense™ 10 Elite CPAP Machine with HumidAir™ Heated Humidifier

Automatically adjusts therapy to respond to your breathing

Built-in humidifier prevents dryness and congestion

Eases you into restful sleep with AutoRamp

Daily insights keep you motivated and on-track

Try It For 60 Nights Risk-Free

Product deep dive

A closer look at every feature

From your first breath to long-term therapy — here’s how the AirSense 10 works for you.

How CPAP Works

A Simple Breakdown

New to CPAP? Here’s how the AirSense 10 treats sleep apnea while you sleep.

Your AirSense 10 generates pressurized air

The whisper-quiet motor draws in filtered air and pressurizes it to keep your airway open throughout the night.

Air travels though tubing to a mask of your choice

The mask seals over your nose, mouth, or both, depending on the type. A good mask fit is the key to comfortable, effective therapy.

Pressure adjusts automatically as your needs change

Auto-adjusting therapy responds breath-by-breath, which can be especially helpful during allergy, cold, or flu seasons.

Heated humidification adds moisture and comfort

Humidification helps prevent dryness, congestion, and sore throat. Heated tubing is included to maximize comfort and keep humidification consistent.

Smart settings keep you comfortable

Adjustable comfort features help therapy feel more natural and easier to get used to.

Helpful tools support setup and nightly use

Features like SmartStart, Mask Fit, and the myAir™ app help you begin therapy easily, fix leaks quickly, and stay on track over time.

AirSense 10 Overview

Everything we love about the AirSense 10 AutoSet

What is AutoSet?

Learn how auto-adjusting pressure keeps you comfortable.

Heated Humidification

The importance of humidification for successful therapy.

Setup and Starting Therapy

Getting ready for your first session.

AirSense 10 Overview

Everything we love about the AirSense 10 AutoSet

What is AutoSet?

Learn how auto-adjusting pressure keeps you comfortable.

Heated Humidification

The importance of humidification for successful therapy.

Setup and Starting Therapy

Getting ready for your first session.

See which machine is the best match for you

BEGINNER FRIENDLY

Resmed Airsense 11 AutoSet

4.5

(622 reviews)

Adjusting to CPAP is easier than ever with weekly Care Check-Ins, Test Drive therapy sessions, and an expanded coaching library.

Richard H.

Verified Buyer

"I love it! Easy starts, not loud at all, seems to respond better than my 10. Suggest trying this if you have been using the 10 for years like me. You won’t regret it!"

Quiet

Easy Setup

TOP SELLER

Resmed Airsense 10 AutoSet

4.8

(879 reviews)

Reads your breathing in real time, adjusts pressure to what you need, and keeps things quiet so you (and your bed partner) can sleep.

Robert B.

Verified Buyer

"I am on my second one. The first one was flawless. I have traveled with it, used it in the RV and at home. Highly recommend!"

Quiet

Durable

Travel

BEST VALUE

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React Health G3 X Auto CPAP

First of its kind foam-free engineering, a 5-year warranty, and smart pressure response that adapts to your breathing in real time.

James

Verified Buyer

I am brand new to CPAP. One week into therapy and my experience with the Luna G3x is really great. I have been able to sleep between 6.5 to 9 hours on CPAP.

Quiet

Easy Setup

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FAQs about the ResMed AirSense 10 AutoSet CPAP Machine

Is the AirSense 10 AutoSet loud?

No, the AirSense 10 AutoSet is one of the quietest CPAP machines available. It operates at just 26.6 decibels, which is quieter than a soft whisper, making it ideal for light sleepers or those with bed partners.

Can I use my AirSense 10 AutoSet while traveling?

Yes, the AirSense 10 AutoSet is FAA-approved for in-flight use on all domestic and international flights. It's compact and lightweight design makes it easy to pack in your carry-on luggage. Just be sure to remove the water from the humidifier chamber before flying and put the device in Airplane Mode to disable wireless connectivity.

How often do I need to replace the air filter on my AirSense 10 AutoSet?

The AirSense 10 AutoSet has two filters - a disposable fine filter and a reusable standard filter. ResMed recommends replacing the disposable air filter every 30 days and the reusable filter every 6 months. Regular filter changes are important for ensuring your machine delivers clean, effective therapy and operates properly.

What masks work with the AirSense 10?

The AirSense 10 is compatible with all standard CPAP masks that connect to a standard-sized 22 mm CPAP hose. It will not work with masks that were specifically designed for the AirMini Travel CPAP.

Can the AirSense 10 be operated without the water tank?

The water tank needs to be installed for air to run through the machine, but you don't have to put water in the tank for the machine to work. Just make sure you turn your humidification settings off before use without humidification.

Alternatively, you may purchase the optional AirSense 10 side cover, which replaces the water chamber and automatically disables humidity settings. If you're interested in buying the side cover, or need help disabling your humidity settings, give our CPAP Guides a call at 1-800-356-5221.

Can I use the AirSense 10 with supplemental oxygen?

Yes, but you'll need the ClimateLineAir OXY Heated Tube for AirSense 10, which includes an integrated port that you can connect your oxygen supply directly to.

You can also use an Oxygen Enrichment Adapter. It's designed to fit between your machine and tubing, or can be used between your tubing and mask. If you're using heated tubing, the adapter must be placed between your tubing and mask. If you're using unheated tubing, either configuration will work, whichever is your preference.

Please note that if you're using an oxygen concentrator, pulse dose concentrators, which deliver oxygen with each breath, will not work with CPAP. It must provide a continuous flow of oxygen to be used with CPAP.

Is the AirSense 10 water chamber dishwasher safe?

The included water tank is not dishwasher safe and must only be hand-washed. You may purchase the Dishwasher-Safe AirSense 10 Water Chamber separately for added convenience.

4.7
Rated 4.7 out of 5 stars
Based on 295 reviews
Total 5 star reviews: 249 Total 4 star reviews: 24 Total 3 star reviews: 8 Total 2 star reviews: 6 Total 1 star reviews: 8
93%would recommend these products
Customers Talked About
Slide 1 selected
295 reviews
  • Eric C.
    Verified Buyer
    3 minutes ago
    Reviewing
    ResMed AirSense 10 AutoSet CPAP Machine
    Rated 5 out of 5 stars
    Great Machine

    This unit was so easy to set up and figure out. Got a great price too

  • James K.
    Verified Buyer
    3 days ago
    Reviewing
    ResMed AirSense 10 AutoSet CPAP Machine
    Rated 5 out of 5 stars
    ResMed AirSense 10 AutoSet CPAP Machine

    Easy to set up and works just fine!

  • BILLY R.
    Verified Buyer
    3 days ago
    Reviewing
    ResMed AirSense 10 AutoSet CPAP Machine
    Rated 5 out of 5 stars
    Very quiet and easy to operate.

    This Airsense 10 is a very simple machine to operate. It also much quieter than my previous unit. the Myair app is also nice for tracking your sleep times and quality.

  • Adam S.
    Verified Buyer
    5 days ago
    Reviewing
    ResMed AirSense 10 AutoSet CPAP Machine
    Rated 5 out of 5 stars
    Great machine - Super quite and comfortable.

    This is actually the second ResMed AirSense 10 I have purchased. Cpap.com made it super easy.

    My current machine is almost a decade old and it is time to replace it, and it has been such a good machine for me, I decided to buy another one.

  • George W. C.
    Verified Buyer
    1 week ago
    Reviewing
    ResMed AirSense 10 AutoSet CPAP Machine
    Rated 5 out of 5 stars
    New AirSense 10 CPAP machine

    Answered all my questions. Quick ship received in two days.

We are experts in what we do

25+ years of sleep apnea expertise, 2+ million masks personally fitted, and 500,000+ CPAP machines set to prescription. Our Sleep Specialists are here when you need them.

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There's no better machine to start therapy with. Try it for 60 nights.