React Health
MPN: G4600
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React Health G3 X Auto CPAP Machine
  • React Health G3 X Auto CPAP Machine
  • React Health G3 X Auto CPAP Machine
  • React Health G3 X Auto CPAP Machine
  • React Health G3 X Auto CPAP Machine
  • React Health G3 X Auto CPAP Machine
  • React Health G3 X Auto CPAP Machine
  • React Health G3 X Auto CPAP Machine
  • React Health G3 X Auto CPAP Machine
React Health G3 X Auto CPAP Machine
React Health G3 X Auto CPAP Machine

React Health G3 X Auto CPAP Machine

$873.00

This product requires a prescription before shipment.

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Product Overview

Meet the new G3 X APAP. With first of its kind foam-free engineering, a 5-year warranty, and smart pressure response that adapts to your breathing in real time, every detail is designed to give you peace of mind — even the price.

Whether you’re upgrading from an older machine or starting CPAP for the first time, the G3 X will have you sleeping comfortably and in control from the very first breath.

What's Included
  • G3 X APAP Machine
  • Heated Tubing (G4600 model only)
  • Water Chamber
  • Power Supply
  • Disposable Filter
  • Travel Bag
  • G3X - User Manual
  • Your order comes with everything needed to safely power and run your machine. However, your mask must be purchased separately.
What Masks Can I Use?

The G3 X works with most standard CPAP masks from any major manufacturer, including nasal, nasal pillow, and full-face masks.

Already have a mask? It will almost certainly work unless it was designed for the AirMini travel CPAP.

Starting fresh? Our CPAP Guides can match you to the right fit.

Shipping & Support

CPAP.com Guarantee
60-day returns — even if used. Full refund (excl. shipping fees). Contact our CPAP Guides to start a return.

  • Free shipping on orders over $50 to all 50 states. Orders before 4 PM CST (Mon–Fri) ship same day.
  • Arrives in 5–10 business days via ground shipping.
  • 2-year warranty from Resmed covering defects in materials and workmanship.

Federal law requires us to have a valid prescription on file before we ship your item. Don't have a prescription? Don't worry — we can help. Expired? We'll help you renew it.

Have questions?

Our CPAP Guides are here for you.
Call 1-800-356-5221

Foam-free performance designed for long-term peace of mind.

Built differently, on purpose

The G3 X is the first standard-size PAP available in the US engineered completely foam-free. No degrading materials, nothing to off-gas, nothing between you and clean therapeutic air. With a best-in-class 5-year warranty, and a price that may surprise you, you can commit to therapy with confidence.

  • Best-in-class 5-year warranty
  • First foam-free standard-size PAP in the US
  • No foam degradation or particle off-gassing
  • Costs less than you'd think

Less dryness, more comfort

An integrated heated humidifier helps reduce dryness and congestion, with five humidity levels plus an Auto mode that adjusts to your environment. The water chamber removes easily for a quick daily rinse and a deeper weekly clean. For steadier humidity and fewer condensation issues, add the optional G3 X Heated Tubing. It offers five heat levels and helps keep water from building up in your hose. 

  • Five humidity levels plus Auto mode
  • Easy-remove water chamber for quick cleaning
  • Reduces dryness and congestion
  • Compatible with most CPAP mask
  • Quiet enough for light sleepers and partners

Therapy that isn't one-size-fits-all

Getting used to CPAP shouldn't be a struggle. The G3 X adjusts pressure to your exact needs for an easier transition into therapy. Smart A adapts to your breathing over a rolling five-session window, while Reslex pressure relief takes the work out of exhaling.

  • Auto-adapts to your sleep apnea needs
  • Reslex makes exhaling feel natural
  • Eases you into therapy as you fall asleep
  • Connected features keep you on track
First Week Tips
  1. Try Reslex and Auto Ramp to ease into therapy; adjust gradually as needed.
  2. Set your mask type and run the built-in mask fit test before your first full night.
  3. Fill the water chamber with distilled water and empty it daily for best hygiene.
  4. Add heated tubing for steadier humidity and fewer mid-night adjustments.
  5. Check out the full lineup of Luna G3X replacement parts and accessories to stay on schedule.

Ready for travel too: the G3X is FAA compliant for in-flight use and supports built-in 4G cellular connectivity for on-the-go therapy insights.

For more setup and first-use tips, read our review or check out the G3X user manual.

Compatibility and Quick Setup

The Luna G3X connects to any standard 22mm CPAP mask, regardless of brand. To optimize humidification, match the tube setting to your hose type; consider upgrading to heated tubing if your room is cool or dry. Access the user manual here.

How APAP Works

New to APAP? Here’s how the G3 X treats sleep apnea while you sleep.

  1. Your G3 X generates pressurized air to a mask of your choice
    The machine quietly filters air and pressurizes it to help keep your airway open throughout the night.
  2. Pressure automatically adapts to your changing needs
    Exclusive to the G3 X, Smart A technology personalizes therapy by adapting pressure based on your recent sleep sessions.
  3. Humidification adds moisture for comfort
    Integrated humidification helps reduce dryness and support more comfortable nightly therapy, which comes in handy during cold, flu and allergy seasons.
  4. Heated tubing keeps airflow consistent and comfortable
    The heated tubing system helps regulate temperature and humidity throughout the night, so you can sleep uninterrupted.
  5. Connected tools support long-term success
    Built-in connectivity and patient support tools help simplify setup, therapy tracking, and ongoing care, making it easier to stay on top of things.

Comfort Features
  1. Smart pressure response
    G3 X's proprietary Smart A technology adapts therapy over a rolling 5-session window to respond to your changing needs.
  2. Humidification designed for comfort
    Built-in humidification helps reduce dryness and irritation.
  3. Heated tubing support
    The G3 X includes heated tubing to help maintain moisture consistency and improve comfort throughout the night.
  4. First-of-its-kind foam-free design
    The G3 X was engineered without polyurethane foam while still delivering dependable, quiet therapy, thanks to its unique honeycomb design.
  5. Simple setup and navigation
    Intuitive controls makes setup easier for both new and experienced PAP users.
  6. Long-term peace of mind
    Backed by the industry's only 5-year warranty, the G3 X is built to support years of reliable therapy.

Stay Connected

The G3 X includes simple tools to help you set up therapy, track progress, and stay engaged.

  1. Built-in 4G connectivity
    Wireless connectivity allows therapy data to sync with cloud-based platforms for ongoing support.
  2. Provider-to-patient messaging
    You’re not alone. Connected care tools allow communication between providers and patients to help support therapy success.
  3. iCodeConnect compatibility
    Get therapy insights and support tools through React Health’s connected ecosystem.

Full Specifications

Here are the key technical details and performance highlights for the G3 X APAP.

  • Therapy Type: Auto-adjusting PAP (APAP)
  • Model: AutoCPAP
  • Pressure Range: Up to 40 cmH₂O
  • Foam-Free Construction: Yes
  • Warranty: 5 years
  • Connectivity: 4G, cloud platform, iCodeConnect
  • Humidification: Integrated humidification
  • Heated Tubing: Included with G4600 model
  • Pressure Response Technology: Smart A
  • Compatibility: Standard CPAP masks and tubing
  • Model: G4600 (with heated tubing)
Specifications
Vendor Product Number G4600
Tax Category RX Machine
Billing Code E0601 (CPAP)

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Product image for 3B Medical Luna G3 Auto Machine With Heated Humidifier

React Health G3 X Auto CPAP

First of its kind foam-free engineering, a 5-year warranty, and smart pressure response that adapts to your breathing in real time.

James

Verified Buyer

I am brand new to CPAP. One week into therapy and my experience with the Luna G3x is really great. I have been able to sleep between 6.5 to 9 hours on CPAP.

Quiet

Easy Setup

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FAQs about the React Health G3 X Auto CPAP Machine

What makes the G3 X APAP different from other PAP machines?

The G3 X APAP is the first standard-size foam-free PAP available in the U.S.* and includes a category-leading 5-year warranty along with connected care features and adaptive therapy technology.

Does the G3 X use polyurethane sound-abatement foam?

No. The G3 X was engineered without polyurethane sound-abatement foam.

What is Smart A technology?

Smart A is the G3 X’s adaptive pressure response technology that adjusts therapy over time based on your recent sleep sessions.

What masks work with the G3 X APAP?

The G3 X APAP is compatible with standard CPAP masks and standard CPAP tubing.

Can providers monitor therapy remotely?

Yes. The G3 X includes connected care features with cloud-based therapy management and provider-to-patient communication tools.

How long is the warranty?

The G3 X includes a 5-year warranty on the main device.

Is the G3 X loud?

The G3 X is designed to provide comfortable nightly therapy while operating quietly during normal use - 28 dB(A) sound pressure level when operating at 10 cmH₂O. Patients on higher pressures (15+) will experience more noise.

Can I travel with the G3 X?

While not specifically built for travel, the G3 X can still be packed up and brought along when needed. Be sure to empty the water chamber before transport and store the machine securely using the included travel bag. For CPAPs designed for travel, shop here.

React Health G3 X Auto CPAP Machine

$873.00

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