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Auto CPAP Machines (APAP machines)

APAP machines offer two positive airway pressure modes—auto-adjusting and continuous—and adapts to your lifestyle by helping with allergies or weight changes to maximize your comfort. Shop our many APAPs from industry-leading manufacturers to meet your sleep apnea needs.


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APAP machines offer two positive airway pressure modes—auto-adjusting and continuous—and adapts to your lifestyle by helping with allergies or weight changes to maximize your comfort. Shop our many APAPs from industry-leading manufacturers to meet your sleep apnea needs.


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Product image for ResMed AirSense™ 10 AutoSet™ CPAP Machine with HumidAir™ Heated Humidifier

ResMed AirSense™ 10 AutoSet™ CPAP Machine with HumidAir™ Heated Humidifier

★★★★★
818 Reviews
$999.00 $1099.99
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Save $119.00
Product image for AirMini™ AutoSet™ Travel CPAP Machine - FREE Mask Included!

AirMini™ AutoSet™ Travel CPAP Machine - FREE Mask Included!

★★★★★
633 Reviews
$880.00 $999.00
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Product image for AirMini™ Travel CPAP Machine Bundle with FREE AirFit™ P10 Nasal Pillow Mask

AirMini™ Travel CPAP Machine Bundle with FREE AirFit™ P10 Nasal Pillow Mask

★★★★★
5 Reviews
$880.00 $999.00
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Save 25%
Product image for Luna II Auto CPAP Machine with Humidifier

Luna II Auto CPAP Machine with Humidifier

★★★★★
62 Reviews
$849.00 $1129.00
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Product image for AirSense 10 AutoSet with Heated Humidifier + P10 Nasal Pillow Mask Bundle

AirSense 10 AutoSet with Heated Humidifier + P10 Nasal Pillow Mask Bundle

★★★★★
4 Reviews
$1099.00 $1149.99
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Product image for AirSense 10 AutoSet with Heated Humidifier + P30i Nasal Pillow Mask Bundle

AirSense 10 AutoSet with Heated Humidifier + P30i Nasal Pillow Mask Bundle

★★★★★
1 Review
$1099.00 $1149.99
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Product image for AirSense 10 AutoSet with Heated Humidifier + Aifit N30i Nasal Mask Bundle

AirSense 10 AutoSet with Heated Humidifier + Aifit N30i Nasal Mask Bundle

★★★★★
6 Reviews
$1099.00 $1149.99
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Product image for F&P SleepStyle™ Auto CPAP Machine

F&P SleepStyle™ Auto CPAP Machine

★★★★★
6 Reviews
$999.00
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Product image for Somnetics Transcend 3 Auto miniCPAP

Somnetics Transcend 3 Auto miniCPAP

★★★★★
15 Reviews
$599.00
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Product image for Transcend 365 Auto CPAP

Transcend 365 Auto CPAP

★★★★★
9 Reviews
$799.99
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Product image for Z2 Auto Travel CPAP Machine

Z2 Auto Travel CPAP Machine

★★★★★
92 Reviews
$579.00
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Save $119.00
Product image for AirMini™ Travel CPAP Machine Bundle with FREE AirFit™ F20 Full Face Mask

AirMini™ Travel CPAP Machine Bundle with FREE AirFit™ F20 Full Face Mask

★★★★★
1 Review
$880.00 $999.00
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Product image for Luna II Auto CPAP Machine with Mask Bundle

Luna II Auto CPAP Machine with Mask Bundle

$899.00
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Product image for DreamStation 2 Auto CPAP Advanced with Humidifier

DreamStation 2 Auto CPAP Advanced with Humidifier

★★★★★
5 Reviews
$1205.00
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Save $119.00
Product image for AirMini™ Travel CPAP Machine Bundle with FREE AirTouch™ F20 Full Face Mask
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Product image for iCH II Auto CPAP Machine with Built-In Heated Humidifier

iCH II Auto CPAP Machine with Built-In Heated Humidifier

★★★★★
20 Reviews
$529.00
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Product image for AirMini™ Travel CPAP Machine Bundle with FREE AirFit™ F30 Full Face Mask
Free Shipping
Save $119.00
Product image for AirMini™ Travel CPAP Machine Bundle with FREE AirFit™ N20 Nasal Mask

AirMini™ Travel CPAP Machine Bundle with FREE AirFit™ N20 Nasal Mask

★★★★★
3 Reviews
$880.00 $999.00
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Save $100.99
Product image for AirSense™ 10 AutoSet™ For Her CPAP Machine with HumidAir™ Heated Humidifier

AirSense™ 10 AutoSet™ For Her CPAP Machine with HumidAir™ Heated Humidifier

★★★★★
130 Reviews
$999.00 $1099.99
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Save $150.00
Product image for 3B Medical Luna II QX Auto CPAP with Heated Humidifier

3B Medical Luna II QX Auto CPAP with Heated Humidifier

★★★★★
1 Review
$699.00 $849.00
Product image for GoodKnight 420E Auto CPAP Machine

GoodKnight 420E Auto CPAP Machine

★★★★★
83 Reviews
Product image for REMstar Auto C-Flex CPAP Machine

REMstar Auto C-Flex CPAP Machine

★★★★★
55 Reviews
Product image for Zzz-PAP Auto CPAP Machine with Therapy Software

Zzz-PAP Auto CPAP Machine with Therapy Software

★★★★★
51 Reviews
Product image for ResMed S8 AutoSet Vantage™ EPR™ Auto CPAP Machine

ResMed S8 AutoSet Vantage™ EPR™ Auto CPAP Machine

★★★★★
70 Reviews
Product image for M Series Auto CPAP Machine with C-Flex

M Series Auto CPAP Machine with C-Flex

★★★★★
124 Reviews
Product image for S8 AutoSet™ II CPAP Machine

S8 AutoSet™ II CPAP Machine

★★★★★
113 Reviews
56 items |

Learn About Auto Adjusting CPAP Machines

Searching for a device that will change and grow with you? Look no further! APAP machines have been rated one of the most comfortable devices due to their unique ability to automatically adjust with each breath and deliver your ideal pressure throughout the night.

Why buy an APAP machine (Auto CPAP machine)?

If you're new to CPAP therapy or simply looking to upgrade your machine, an auto CPAP machine can be slightly more expensive, but the benefits can be worth the investment.

  1. Are you an active sleeper? Tossing and turning at night alters your breathing pattern. Having a machine that auto adjusts to your sleeping position can reduce apnea events.
  2. Do you have allergies or congestion? No worries, with a machine that automatically detects your breathing levels, you will have effective CPAP therapy year round.
  3. Weight loss or weight gains? Whether you have your eyes set on losing weight or have weight gains due to other complications, your machine will adjust with you.
  4. Are you struggling with your regular CPAP machine? The constant flow of a CPAP machine can be uncomfortable for sleep apnea patients. An APAP machine that feels more natural to your breathing needs may be a better fit for you.
  5. Looking for the best of both worlds? The flexibility of an APAP machine also allows you to choose between continuous pressure (CPAP) and automatic (APAP) mode with the same machine.

If you have cardiovascular complications, central sleep apnea, or hypoventilatory disorders, an APAP machine is not recommended. Although auto CPAP machines can provide more comfort, consulting with your doctor on what pressure range best suits you is key to success.

Learn more about the differences between Auto CPAP vs CPAP and how an APAP machine can benefit you.

Customer Highlights on Popular APAP Machines:

The best APAP machine so far (AirSense 10 AutoSet)

"I just purchased the Resmed Airsense 10 AutoSet to replace my old Resmed CPAP. I can't believe how quiet it is. I was able to adjust to the new style of automated pressure the first night. I find that I am sleeping better. I toss and turn at night and have tried various nasal masks. I would experience mask leaks due to the constant high pressure. With the AutoSet, It reads my sleep and provides the pressure I need when I need it and as such did not need a new prescription. The APP function is quite useful. I can rate my sleep and keep track of the number of apnea events I experience."

My First Machine (AirSense 10 AutoSet)

"I was just diagnosed with sleep apnea, and this is the machine that was prescribed by my doctor. After doing some research, I learned that this is one of the most advanced and flexible machines that one can buy. It can be set for auto or CPAP and has all the comfort features like a humidifier, heated hose, and expiratory pressure relief. It is a 'smart' machine that will detect your breathing patterns and adjust accordingly. After a week, I've had absolutely no problems with it. Happy so far."

Unbelievable (AirSense 10 AutoSet)

"I LOVE this machine! I had my last one for 15 years!! Needless to say, it needed replacing. It is so quiet I have to check to make sure it is on. While my nights were restful before, I would wake up with a dry mouth a couple of times a night most nights. This machine is so gentle that it does not feel like a blast of air to get used to. I would highly recommend this machine with adjustable pressure to everyone. Sleep tight :)"

Incredible (Luna II Auto CPAP machine)

"What a huge improvement over my old Respironics System One. I can sleep the entire night. The auto setting is a lifesaver, as it adjusts automatically to your needs. The humidifier gets warm moist air to you pretty quickly. The backlit display tells you everything and is very easy to set up, and I couldn't pass up the price. Thank you CPAP.COM !"

Great product (Luna II Auto CPAP machine)

"I was looking for a lower cost auto CPAP machine. This was the ticket. I was very surprised at the features and the quietness of the unit. I have slept great. With the sale that CPAP.com had going on, this unit was very affordable. Also, CPAP.com also setup the unit for me. Great customer service. The unit is very easy to use, feels and sounds of good quality. Very quiet at night when in use. Simple controls. A little bigger than my other unit, but that is not an issue for me. Came with a tube, manuals, a nice carry bag, and cords. Really, this is a nice unit."

In love (AirSense 10 For Her AutoSet)

"After using a regular CPAP and gaining some weight, the CPAP no longer worked for me and my doctor figured I needed a higher air setting but my insurance would not cover another titration! So, I tried the APAP machine, and OMG where has this thing been all my life?!!!! I’m finally sleeping again and no longer feel like a member of the walking dead! Seriously-it was so bad I was falling asleep while driving before I was diagnosed with OSA. Way better than a regular CPAP because it adjusts to what your body needs throughout the night!"