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The Best CPAP Cleaning Machines Reviewed in 2022

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There are a variety of CPAP cleaners on the market, but not all the options available are created equal. To help you find the best CPAP cleaning machine for your CPAP equipment, we evaluated numerous products based on ease of use, effectiveness, customer satisfaction, and our own experiences. We found the LiViliti Paptizer to be the best CPAP cleaning machine overall due to its easy-to-use design, multiple function modes, and unique drying and storage capabilities.

Quick Look at the Best CPAP Cleaners

Not only can dirty CPAP equipment reduce the efficacy of your sleep apnea treatment, but using an unclean CPAP mask or hose could even cause you to become ill. Potential risks of using unclean equipment include direct exposure to bacteria, molds, and viruses that cause colds, sinus infections, and even pneumonia. Regularly cleaning your sleep apnea equipment is just as important as brushing your teeth and changing the oil in your car.

We know life gets busy, which is why we selected the LiViliti Paptizer as our top pick for the overall best CPAP cleaning machine. The Paptizer kills 99.9% of germs, bacteria, viruses, and pathogens—without any chemicals—in just three minutes. Additionally, it can be used as 24-hour sanitized storage and is even capable of drying small amounts of water leftover from your regular cleaning routine. While you’ll still need to wipe your mask down to clear it of oils and skin cells, the Paptizer finishes the drying process and can have your sanitized equipment waiting for you when it’s time to wind down for bed.

How We Chose the Best CPAP Cleaning Machines

There are quite a few CPAP cleaning machines on the market, and some of the products available across the United States, namely ozone cleaners, are not helpful and can even be harmful to your health. In 2020, the FDA issued a communication about the safety and effectiveness of both ozone and UV cleaners, making it clear that neither had been tested nor approved for cleaning CPAP equipment.

The use of ozone cleaners can void equipment warranties and has been shown to exacerbate asthma and other respiratory illnesses when not fully cleared from the system. Since the only real danger associated with UV is prolonged exposure, we feel comfortable using and recommending the UV CPAP sanitizers in this article because they completely enclose the equipment and shield the user from exposure.

For your consideration, we’ve rounded up our top six best CPAP cleaning machines and products for safely disinfecting and maintaining your CPAP equipment. As you’ll see, we’ve detailed the features and benefits of each product, so you have a full picture of the top CPAP cleaning supplies available to you.

Skip ahead: Curious about Ozone vs. UV CPAP cleaners?

Whether you’re ready to establish a new cleaning routine or you want to strengthen your current sanitation schedule, the product recommendations below are designed to promote healthy habits and help improve your CPAP experience night after night.

Are CPAP Cleaning Machines Necessary?

CPAP cleaning machines are designed specifically for use with your CPAP equipment and will ensure that it remains in working order while also protecting you from bacteria, mold, and illness-causing viruses that could live on your CPAP mask or in your tubing.

People have been successfully treating OSA with CPAP machines for decades and have gotten along just fine without CPAP cleaning machines. That said, these devices are meant to reduce the amount of time you spend cleaning your equipment. Each has its pros and cons and specific use cases, so it’ll be up to you to determine the best products to have on hand for your cleaning needs.

Keep in mind, though, that the best CPAP cleaning routine is a multi-step process regardless of the devices or products you choose to incorporate into your daily schedule; there simply is no one-stop cleaning solution for CPAP supplies, and not even our top pick, the LiViliti Paptizer, is capable of handling 100% of your cleaning routine. We hope that you’ll have a good experience working one or some of these products into your routine and that they can help make therapy a bit more manageable for you as a whole.

Without further ado, let’s take a look at our top picks.

Best Overall CPAP Cleaner

LiViliti Paptizer UV CPAP Sanitizer 

Image of the paptizer cpap cleaning machine
LiViliti Paptizer UVC LED Smart CPAP Sanitizer

New to the CPAP.com catalog, the LiViliti Paptizer has impressed us in multiple areas compared to the previous king of UV sanitization, the Lumin CPAP Cleaner. While not quite as simple as the Lumin’s single button and cleaning cycle, the Paptizer’s design is still very straightforward and easy-to-use, and even includes a built-in carrying handle!

There are two major areas where the Paptizer excels over the Lumin: the versatility of its three function modes and LiViliti’s sheer commitment to thorough UV sterilization. Where the Lumin features one mercury-arc UVC quartz bulb, the Paptizer is equipped with 40 UVC LEDs strategically spaced around the interior of the unit. These LEDs are rated for 10,000 hours of usage and will automatically turn off if the lid is opened during a sanitizing cycle.

The three modes of operation offered by the Paptizer are Fast Sanitize, Fast Sanitize and Sanitized Storage, and Auto Mode. The Fast Sanitize function will run a 3-minute sanitizing cycle after which your equipment will be immediately ready for use. With the Fast Sanitize and Sanitized Storage option, your equipment will undergo the same initial 3-minute sanitizing cycle before switching to a low-light storage option that will keep your equipment sanitized for up to 24 hours or until the lid is opened again.

Finally, there’s the Auto Mode, which enters a 60-minute smart drying cycle after the initial 3-minute sanitizing cycle. Using an onboard fan and sensor, the Paptizer will remove small amounts of water leftover from your routine cleaning. If your equipment is not dry after the 60-minute cycle, the device will determine if another 30, 60, or 90-minute drying cycle is required.

The Paptizer is the most versatile CPAP cleaner out there because of its unique drying and storage modes and can even be used to sanitize cell phones, dentures, hearing aids, computer mice, and just about anything else you can fit inside of it! The only real drawback is that you’ll still need to use a tube brush to effectively clean the inside of your CPAP hose.

Best UV CPAP Sanitizer

3B Medical Lumin CPAP Cleaner

Lumin CPAP Mask & Accessories Sanitizer

If you’re looking for a high-quality reliable UV CPAP sanitizer but aren’t concerned about drying equipment, you can’t go wrong with the Lumin CPAP Cleaner. Like the Paptizer, the Lumin uses UVC light to eliminate bacteria and pathogens from your CPAP equipment, cell phone, or anything else that fits inside the drawer. While the Lumin CPAP Cleaner is a powerful device, it should be used to sanitize your CPAP equipment in addition to your regular cleaning routine. Using wipes (including a citrus-scented option) to clear your mask of saliva, skin cells, and facial oils is a great way to prep it before using the Lumin to sanitize. To make cleaning easier to fit into your daily life, we carry a wide range of cleaning wipes that encourage ongoing tidiness. 

To use the Lumin CPAP Cleaner, which features a mercury-arc germicidal lamp that emits UV light, simply plug the device into a wall outlet then open the drawer and place your CPAP mask and CPAP accessories inside. Once you have completed the initial set-up, there isn’t any ongoing maintenance for this product aside from occasionally wiping down the inside as needed. Another perk of this product is that your CPAP equipment can be used immediately after the cleaning cycle. This is especially helpful if you are unable to clean the components of your CPAP setup until bedtime. 

While it isn’t necessarily a one-stop washing machine for your CPAP equipment, the Lumin deserves recognition for its sanitizing power and versatility. While the Paptizer certainly has the edge thanks to its multiple cycles and drying functionality, the Lumin should not be overlooked and is a great UV CPAP sanitizer if you don’t need a drying mode.

The only drawback of the Lumin CPAP Cleaner is that UV technology can’t clean surfaces it doesn’t come into contact with, so it can’t effectively clean the inside of your tubing. The Lumin Bullet was previously available for hose cleaning but was unfortunately discontinued in March 2021.

For more information about the Lumin CPAP Cleaner, including its purpose and benefits, check out our full Lumin CPAP cleaner review.

Best for Budget-Conscious Shoppers

Republic of Sleep Universal Premium Cleaning Bundle

Republic of Sleep Universal Premium Cleaning Bundle

Killing 99.9% of bacteria and viruses on contact, the Universal Premium Cleaning Bundle from Republic of Sleep includes hospital-grade products at a fraction of the price. While it isn’t actually a cleaning machine, this cleaning toolkit is the best low-priced CPAP cleaner and is perfect if you prefer a more analog approach—no buttons, cords, or UV light required.

This cleaning bundle includes:

  • Control III Hospital-Grade Sanitizing Cleaner (Concentrate)
  • Republic of Sleep Citrus Mask Wipes (75)
  • Republic of Sleep Tube Brush
  • Outlet Bacteria Filter (10 Pack)

The 16-ounce bottle of Control III Sanitizing Cleaner in this package makes 16 gallons of cleaning product, so you’ll be set for several months before you need to restock. When paired with the Control III Sanitizing Cleaner, the included citrus-scented wipes help you achieve a powerful clean across all of your CPAP components.

For the microscopic germs in your tubing that traditional brushes may miss, the included durable but flexible silicone of the Republic of Sleep Tube Brush lets you maneuver around all the tiny nooks and crannies of your CPAP tubing to remove debris with ease.

Finally, the 0.3 Micron-sized filter boasts a 99.97% filtration rating and helps block out allergens, hair, dust, and dander. However, this product should not be used if you are prescribed a CPAP pressure setting of 7cm H2O or less. Some machines will have a setting that adjusts pressure when a bacterial filter is used, so be sure to consult your user manual or give us a call if you have any questions.

The Republic of Sleep Universal Premium Cleaning Bundle is a solid pick for some, and its only real drawback is that it isn’t a permanent solution. Unlike a UV CPAP sanitizer, this kit will need to be regularly replenished throughout your sleep apnea journey. For your convenience, each item in this bundle can also be purchased individually.

Best Portable CPAP Cleaner for Traveling

Travel-Sized Control III Disinfectant CPAP Cleaning Solution

2 oz Travel-Sized Control III

While the LiViliti Paptizer is our top pick for everyday sanitization at home, it may not be the best option for your next excursion—especially if you’re trying to save room in your suitcase for souvenirs from your travels.

The Travel-Sized Control III Hospital-Grade Sanitizing Cleaner is a powerful and effective disinfectant approved by the EPA for sanitizing a variety of CPAP equipment, including masks, tubing, and humidifier chambers. We consider this product the best portable CPAP cleaner, particularly for frequent travelers.

When properly diluted, the Control III Disinfectant CPAP Cleaning Solution can safely sanitize your CPAP equipment. (Note: Never use the concentrated disinfectant straight out of the bottle.) In just 10 minutes, this product kills 99.9% of all bacteria, germs, and viruses, including:

  • Herpes Simplex Virus Type 1 and 2
  • Influenza Virus Type A
  • HIV 1 (AIDS)
  • E. Coli
  • MRSA
  • Staphylococcus Aureus
  • Pseudomonas Aeruginosa
  • Salmonella Choleraesuis
  • Adenovirus Type 5

A full-sized bottle is also available if you prefer to keep a larger supply of disinfectant on hand, and if you really want to be thorough, we even offer testing strips to ensure your solution is potent enough to disinfect. 

This product won’t cause your CPAP equipment to dry out or crack, and it can be especially useful if you’re currently fighting a cold. For a cost-effective solution for on-the-go transportation, the Travel-Sized Control III Disinfectant CPAP Cleaning Solution is a good choice.

Best CPAP Hose Cleaner

Republic of Sleep CPAP Tube Cleaning Brush

cpap hose cleaning brush
ROS CPAP Tube Cleaning Brush

There’s really no dispute when it comes to cleaning the inside of your CPAP hose: a tube brush is your best bet. When it comes to tube brushes, however, many members of the CPAP community have some feedback that’s been specifically addressed by the ROS CPAP Tube Cleaning Brush. 

Traditionally, a CPAP tube brush is a long piece of wire, typically braided, that has bristles on one end for cleaning the inside of your CPAP hose. While the stiffness of the wire is suitable for brushing and detailing a specific area inside the hose, those with heated hoses or 90-degree connections report having difficulty thoroughly cleaning their hose with standard metal tube brushes. 

The second major complaint is regarding the stiffness of the bristles used. While these bristles are designed to thoroughly clean without damaging the tube, some people have had issues with the bristles degrading their tube over time, resulting in a leaky hose that needs replacing. 

Enter the ROS Tube Brush, which features ten soft silicone bristles that clean the ridges inside of your tube without damaging it. The brush also uses a weighted ball to drop down through the hose rather than needing to be pushed through it, allowing a better cleaning experience for those with heated tubing or 90-degree connections. To use, you’ll first add a small amount of water and your choice of mild soap or cleaning solution into the hose, then drop the weighted ball through your hose until it reaches the other end. Then simply tug the brush through until it’s pulled out the other side, rinse out the hose, rinse off the brush, hang both up to dry, and call it a day!

If you don’t believe us, there’s no shortage of 5-star reviews from pleasantly surprised CPAP owners who have struggled to clean their heated tubing or had issues with metal brushes in the past. 

Best CPAP Hose Dryer

Hurricane CPAP Equipment Dryer

Hurricane CPAP Equipment Dryer

The most time-consuming part of regular CPAP cleaning and maintenance is simply allowing your hose time to dry in the morning if you use a humidifier. This critical step should not be overlooked because warm, wet environments are breeding grounds for bacteria. 

It’s not uncommon to find that your equipment still has a bit of moisture on or in it despite being cleaned and hung to dry several hours ago. The Hurricane CPAP Equipment Dryer allows you to simply place your mask, cushion, humidifier chamber, and hose into the basket and set a 15, 30, or 60-minute drying cycle, then go about your day. When you’re ready to wind down for bed that evening, all of your equipment will be clean, dry, and sterilely stored, awaiting your return. 

While the Hurricane is perfectly capable of drying all of your CPAP equipment (including soaking wet headgear), where it really shines is in hose drying. There’s a unique connection point for your tubing (assuming you have at least one standard 22mm tubing end) to ensure maximum airflow throughout the entire tube. Warm air will also circulate through the entirety of the device, drying all of your supplies simultaneously; the 60-minute cycle should easily handle every part of your setup that needs drying.

It’s also somewhat versatile when not being used to dry your CPAP supplies. It’s a great way to sterilely dry and store baby bottles, pacifiers, and other high-use items that may require cleaning cycles with a quick turnaround. The Hurricane uses a reusable foam filter that can be washed and replaced and is compatible with most tubing, including heated tubing.

Ozone vs. UV CPAP Cleaners: Why We Don’t Recommend SoClean

We intentionally do not carry ozone cleaning products—also known as activated oxygen cleaning products—including items like the SoClean 2 and SoClean 3. Ozone exposure can be dangerous for those who have certain respiratory conditions like sleep apnea and asthma. In fact, the Environmental Protection Agency (EPA) says various levels of ozone exposure can “cause coughing, pain when taking a deep breath, inflame[d] airways, [and an] increase [in] the frequency of asthma attacks.” 

Additionally, according to the Food and Drug Administration (FDA), ozone is a “toxic gas with no known useful medical application.” The FDA continues, “In order for ozone to be effective as a germicide, it must be present in a concentration far greater than that which can be safely tolerated by man and animals.” 

It’s also worth noting that in February 2020, ResMed announced that “any damage caused by exposure to ozone [or] activated oxygen” would not be covered in its included limited warranty, as the company discovered that ozone cleaners may cause internal degradation of CPAP equipment. Instead, the best CPAP cleaner for ResMed AirSense 10 and some other ResMed products would be the Paptizer or the Republic of Sleep Universal Basic CPAP Cleaning Bundle. 

Because of the information provided here, we do not carry SoClean or other ozone cleaning products and we do not consider SoClean to be a safe or effective method of cleaning and maintaining your CPAP machine or equipment. 

CPAP Cleaner Buying Guide

One of the first signs of dirty CPAP equipment is an unpleasant odor akin to mold or mildew. If you frequently get sinus or respiratory infections, it could be another indicator of an unclean CPAP setup.

Regarding a general cleaning schedule, your CPAP mask and cushion should be wiped clean each day. These, along with your CPAP hose, should be washed thoroughly once weekly with soap and water. On top of that, your CPAP mask and tubing should also be replaced twice annually. If you use a CPAP humidifier, the humidifier chamber should be rinsed and refilled daily with distilled water

When shopping for the best CPAP cleaner, there are a few things to consider:

  • Your Schedule: If you’re able to, the best option will always be a full soap-and-water cleaning routine followed by an air-dry of your equipment. If you are often short on time or prefer a more leisurely bedtime routine, a CPAP cleaning machine like the Paptizer or Lumin pairs well with mask wipes for a quick clean and sterilization, though your hose will still require more dedicated care. If drying time is what affects you the most, consider the Hurricane CPAP Equipment Dryer. 
  • Your Budget: CPAP cleaning products can range from $4.95 to around $300, so you’ll need to decide if a larger investment is warranted or if standard cleaning is best for you. Most of the economical cleaner options do need to be replenished every few weeks or months, so it’s worth considering how investing in a UV CPAP sanitizer could save you money in the long run.
  • Your Needs: Some people, such as those who are immunocompromised, may have higher standards for cleaning than others. You should always consider your health and cleanliness needs when shopping for CPAP cleaning supplies, as a CPAP sanitizer like the Paptizer or Control III Disinfectant might be that extra step that helps you to feel totally secure in your cleaning routine.

If you have questions about which product is best for you and your CPAP setup, please leave a comment below! We would love to help you find the product that works best for your needs.

Final Thoughts

For those who ask us what the best CPAP cleaner is, our answer is two-fold: the LiViliti Paptizer is our top pick, though we believe the best CPAP cleaner is the one that fits your CPAP set-up, budget, schedule, and personal needs best. 

It’s crucial to keep your equipment cleaned and sanitized against germs and viruses all year long; especially so in the winter. UV CPAP sanitizers like the Paptizer and Lumin are ideal for those who want to ensure their equipment is clean and thoroughly sanitized. These CPAP cleaning machines add a layer of protection against germs and viruses on top of your regular cleaning routine, though they are not here to replace that routine in its entirety.

If you’re looking for a safe and effective solution for quickly and conveniently cleaning your CPAP equipment, you can order online or by phone at 1-800-356-5221; orders placed before 4 p.m. CST will ship same-day. If you prefer tube cleaning wands or grapefruit/lemon-scented wipes over UV-powered disinfectants, you can order those on CPAP.com, too, where we pass the savings on to you.

For over twenty years, we have researched and stocked the best CPAP equipment from leading manufacturers to help you achieve the comfort and success you deserve throughout your sleep apnea journey. We’re committed to helping you find the right CPAP mask and CPAP machine for your needs. Cleaning your CPAP equipment is almost as important as using your CPAP machine each night. We carry a wide selection of cleaning and comfort accessories and are more than happy to show you how to use CPAP cleaning products if you need assistance.

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