We’re here to help! Call 1.800.356.5221
M-F 8AM-8PM | Sa 8AM-5PM (CST)

Product Review: Z2 Auto CPAP Machine With Scores and Rankings

Table of Contents

Z2 Auto CPAP Machine Review

Human Design Medical’s Z2 Auto Travel CPAP Machine is proving to be quite popular among CPAP users.

The secret? When compared to its predecessor, the Z1 Auto, the Z2 Auto is 29% quieter and has a different pitch to the motor for optimal comfort. An added bonus? It’s an attractive option for busy travelers due to its lightweight and small stature.

How does it stack up against the competition? Let’s find out!

The Z2 Auto Travel CPAP Machine vs Similar Travel Machines

Z2 Auto AirMini DreamStation Go Transcend Auto Z1 Auto
Total 85 81 80 75 80
Noise Level 7 4 4 6 6
Cost 9 9 6 9 7
Warranty 8 8 8 9 9
Weight 9 9 9 9 9
Size 9 9 9 9 9
Pressure Relief 9 9 9 9 9
Therapy Tracking 9 9 9 3 9
Humidification 8 8 8 5 5
Smart Features 8 9 9 8 8
Battery Options 9 7 9 8 9

Add to Cart


Noise Level: 7

The Z2 Auto checks in at 26 decibels and is 29% quieter than the Z1 Auto. However, the pitch of the motor is the showstopper compared to the Z1 Auto. The Z2 Auto is whisper-quiet and sounds similar to quiet background noise while you sleep. This change integrates your therapy into your nighttime routine instead of acting as a disruption. The included Q-Tube Muffler dampens the sound further to create a sleeping environment with fewer interruptions.

Similar Machines’ Noise Level Scores
AirMini 4
DreamStation Go 4
Transcend Auto 6
Z1 Auto 6

Cost: 9

The Z2 Auto is a little more expensive than the Z1 but is still value-priced compared to similar machines in the travel category. It also comes with a lot of nice freebies like a free Q-Tube CPAP Muffler to dampen the sound and a Heat Moisture Exchange Unit (waterless humidification) to keep your nose and throat from drying out.

Similar Machines’ Cost Scores
AirMini 9
DreamStation Go 6
Transcend Auto 9
Z1 Auto 7

Warranty: 8

The two-year warranty is standard when compared to most CPAP machines. It covers manufacturer defects and mistakes but not misuse or abuse. The Z1 Auto has a warranty of three years, which places it as an industry leader. Ultimately, we awarded the Z2 Auto the same score as similar travel machines that also have a two-year warranty.

Similar Machines’ Warranty Scores
AirMini 8
DreamStation Go 8
Transcend Auto 9
Z1 Auto 9

Add to Cart


Weight: 9

The Z2 Auto is so light that you can measure the weight of the machine in ounces and not pounds! It weighs in at 10.4 ounces, which is a nice weight for a travel machine. It weighs roughly the same as the Z1 Auto and others in the travel category. The lightweight of the Z2 Auto allows you to put it in your suitcase or backpack and venture out to your next travel destination.

Similar Machines’ Weight Scores
AirMini 9
DreamStation Go 9
Transcend Auto 9
Z1 Auto 9

Size: 9

If you’re in the market for a travel-friendly CPAP machine, then look no further. The Z2 Auto can be comfortably carried in one hand due to its lightweight and small size. Its tiny size will allow you to fit the machine in almost any bag so that your therapy can travel with you on-the-go. Life’s an adventure—bring your CPAP therapy along with you!

Similar Machines’ Size Scores
AirMini 9
DreamStation Go 9
Transcend Auto 9
Z1 Auto 9

Pressure Relief: 9

The Z2 Auto tracks your breathing on a breath-by-breath basis and automatically adjusts to your correct therapy pressure. The Z2 Auto adapts to your therapy needs, meaning your treatment will never be one-size-fits-all. The auto-adjusting pressure can also save you a trip to the doctor’s office for pressure adjustments.

Along with auto-adjusting pressure, the Z2 Auto also has Z-Breathe Pressure Relief technology, which temporarily reduces the pressure during exhalation and makes it a breeze to exhale. Another benefit? The Z-Breathe technology will help you develop a normal breathing pattern and increase comfortability. The other machines we looked at also have Pressure Relief technology and auto-adjusting pressure so we awarded them a similar score.

Similar Machines’ Pressure Relief Scores
AirMini 9
DreamStation Go 9
Transcend Auto 9
Z1 Auto 9

Add to Cart


Therapy Tracking: 9

Are you a numbers person? Do you like to keep track of how your therapy is going?

The Z2 Auto allows you to download your therapy results right to your Windows computer for further analysis. You can also review your therapy results on your phone using the Nitelog Mobile App. When compared to other travel machines, the therapy tracking features of the Z2 Auto fit right in.

Similar Machines’ Therapy Tracking Scores
AirMini 9
DreamStation Go 9
Transcend Auto 3
Z1 Auto 9

Humidification: 8

The Z2 Auto includes a Heat Moisture Exchange Unit, which is similar to ResMed’s HumidX. The Z2 Auto recycles humidity from your exhaled breath to create the sensation of moisture without needing water-based humidification. This will keep your nose and throat from drying out. The best part? You won’t have to worry about lugging around a separate humidification system or a tank of distilled water while you’re traveling. Just breathe and humidification is made available!

Similar Machines’ Humidification Scores
AirMini 8
DreamStation Go 8
Transcend Auto 5
Z1 Auto 5

Smart Features: 8

The Z2 Auto has auto-start and auto-stop features that are similar to the Z1 Auto. Once you put on your mask, the Z2 Auto detects changes in your breathing and automatically starts. When you wake up, the Z2 Auto will sense your breathing pattern change and automatically stop. That’s one less thing to worry about when you’re on-the-go!

The DreamStation Go and AirMini are comparable to each other in terms of smart features, and the Z2 Auto comes very close.

Similar Machines’ Smart Features Scores
AirMini 9
DreamStation Go 9
Transcend Auto 8
Z1 Auto 8

Add to Cart


Battery Options: 9

If you’re planning on going off-the-grid or are looking to pack a battery back-up just in case, we have you covered. Both the Z1 Auto and the Z2 Auto have a battery that’s been custom-tailored to fit the needs of both machines: the Z1 and Z2 PowerShell Battery. In fact, the Z2 Auto can use all of the Z1 Auto’s same accessories. This is similar to the DreamStation Go, which also has a companion battery that’s designed specifically for it.

You can connect the Z2 Auto to the Pilot-12 Lite with the Z1 and Z2 Mixed Cable Kit. The Portable Outlet CPAP Battery is also an option, which has the capability of powering any device with a power supply and a plug, making it a versatile and flexible battery.

Similar Machines’ Battery Scores
AirMini 7
DreamStation Go 9
Transcend Auto 8
Z1 Auto 9

TOTAL SCORE: 85 / 100

Total Scores for Similar Machines
AirMini 81
DreamStation Go 80
Transcend Auto 75
Z1 Auto 80

Overall, the Z2 Auto scored very well across the board and has made a name for itself compared to similar travel machines. Ultimately, the difference in pitch levels and humidification options are the major factors that separate the Z1 Auto from the Z2 Auto. The option of having a quieter machine with the ability to leave your humidification system at home makes the Z2 Auto hard to beat.

Add to Cart


  • David Repasky

    David Repasky has been using CPAP treatment since 2017 and has first-hand experience with what it's like to live with Sleep Apnea. He brings the patient's perspective to the CPAP.com blog and has received formal training in CPAP machines, masks, and equipment.

Need Help With Sleep Apnea?

Table of Contents

10 Responses

  1. The review was inaccurate with respect to the smart features. The Nitelog app does not function with the Z2. The reviews from users of the Z1 are terrible. The app itself looks like a first generation iPhone app and has not been updated in 3-4 years despite constant complaints from users. Very odd.

    1. Hi Craig, thank you for your feedback. I have contacted Human Medical Design, the manufacturer of the Z1 and was advised that the Nitelog App does in fact work with the Z2. I was also advised that they are in the process of re-designing the Nitelog App. If you are experiencing issues with utilizing the app, please reach Human Medical Design at: 855-436-8729 for technical assistance.

      We value all customer feedback, please feel free to reach us at: 1-800-356-5221 with any further questions, or concerns.

      Enjoy your day!

  2. Hi Craig,
    This may be obvious to everyone but me, but how do I interpret the scores?
    Is 1 the highest or is 10 the highest score?
    Is it possible to upgrade my noisy Z1 to a Z2 without paying full price?
    I can’t even use the Z1 because the noise keeps me awake.

    1. Hi Mike, that’s a great question! For this article, 10 is the highest. The higher the score the better the ranking is.

      Did you purchase your Z1 from CPAP.com within the last 15 days? If so, it is under a guarantee/trial period and you may return it for the Z2 and only pay the difference in cost.

      If you purchased your Z1 from a different company, you should verify what their return policy is.

      Please feel free to reach us at: 1-800-356-5221, or you may e-mail us at: cpap@cpap.com with further questions, or concerns.

      Have a wonderful day!

  3. I have a z1 and an air mini. I would rate the house if the z1 at 3 and the air mini at 9 since you can barely hear the air mini.

  4. I have a Z2 Auto. It’s a very good travel machine, and it is somewhat quieter than the Z1, which I also had prior to the Z2.

    There is still some noise, but it’s much improved. Noise is also impacted by your choice of mask and tube. I found that full size 19mm tubing is quieter.

    Regarding the App – it works exactly the same on the Z2 as the Z1. It definitely needs tweaking. The biggest challenge is getting the app to connect to bluetooth. When you get the connection screen, it seems to see every device in the neighborhood, and the screen scrolls quickly which makes it hard to connect. Once you get the hang of it you can get connected. If you want more data, they have a Win 10 compatible program that has much better data than the mobile app. Having said that, the Nightlog app, and their Windows app have much more info than Resmed My Air. All in all I like the unit.

  5. I am using HDM Auto Z1 since May 19 for my sleep apnea with AHI of 36 . But I am not at all satisfied with this machine as in spite of changing the machine two times by your dealer the AHI is not coming down below 12 . Ideally this should by now would have been below 1. Don’t know what to do and the dealer of the machine in India is equally confused. This small machine is unable to produce pressure more than 8 to 10 in average.
    May be this type of small machine is good for few days in tour to keep AHI in moderate condition and not suitable for regular use. Breas should declare this before it is sold.
    But what about replacement of my machine is not known, a mere waste of $1000 !

    1. Hey Debjyoti, I’m sorry about the difficulty your experiencing with your CPAP therapy. Have you spoken with your doctor regarding your pressure setting? Your doctor should be able to review your sleep therapy data, and make a medical decision to adjust your pressure/machine settings and determine what may be causing your AHI to remain at 12, or higher.

      The Z1 Auto machine, can be used on a regular basis, as the machine operates at pressures just as a regular home-sized machine does.

      Please feel free to contact us if you are in need of any troubleshooting, or if you have questions/concerns, at 1-800-356-5221, or you may e-mail us at: cpap@cpap.com.

      Best Wishes!

  6. buenas tardes, tengo problemas con mi z2 auto, ya que a la segunda semana la aplicación nitelog, no me deja entrar a los resultado de mi terapia vía celular ni utilizando el pc, y lo segundo que cuando inicio mi terapia z2 y ajusto el tipo en apap 2 para que este monitoree mi presión dependiendo de los episodios de apnea que tenga durante la noche, y ultima mente pasa la presión de inicio es de 4.0 y a los diez minutos sube hasta 12 y sigo aun despierto, y mi respiración sigue siendo la misma, no entiendo porque hace esa subida de presión tan drástica si respiro normal mente porque todavía me encuentro despierto, es posible que este aparato se pueda hacer un Reset, e inicial valores nueva mente, haber si se corrige el error; y no tener que enviar el Z2 Auto a una revisión mas profunda, agradezco me puedan responder y colaborar. gracias

    1. Hola Andrés, lamento los problemas que tienes con tu máquina Z2 CPAP. ¿Has intentado desinstalar y reinstalar la aplicación Nitelog? Si no, por favor hazlo.

      Además, para que su ajuste de presión aumente de 4 a 12 mientras está despierto, es posible que tenga una rampa configurada en su máquina.

      Puede desactivar la rampa, si lo desea.

      Desafortunadamente, no hay un botón de reinicio en la máquina, sin embargo, si necesita ayuda para cambiar algunas de las configuraciones en su máquina, estaremos encantados de ayudarle.

      Tenga en cuenta que debe hablar con su médico antes de ajustar su configuración de presión.

      Para obtener más ayuda, preguntas o inquietudes, no dude en comunicarse con nosotros al: 1-800-356-5221, o puede enviarnos un correo electrónico a: cpap@cpap.com.

      ¡Ten un excelente fin de semana!

Leave a Reply

Your email address will not be published. Required fields are marked *

Need Help? 


Need more help? Contact us!

Get help from an expert like Liz

Our experts know CPAP inside and out. Give us a call today and one of our 5 star customer service representatives will help you.

or Text "Help" to 832-308-2219

or Text "Help" to 832-408-9760

Mon-Fri 8am-8pm CST, Sat-Sun 8am-5pm CST